MTGR1 (CBFA2T2) Sheep Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western Blot: 1 - 10 µg/ml.
Reactivity	Human
Host	Sheep
Clonality	Polyclonal
Immunogen	C terminal portion of recombinant protein
Specificity	This antibody reacts to Myeloid Tumor Related Gene (MTGR1) (AML1-MTG8 binding protein or ETH).
Isotype	IgG
Formulation	Phosphate buffered saline with 0.08% sodium azide State: Purified State: Liquid purified Ig (0.2µm sterile filtered)
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	CBFA2/RUNX1 translocation partner 2
Database Link	Entrez Gene 9139 Human UniProt ID O43439
Background	Myeloid tumor related gene (MTGR1) is found deleted in acute myeloid leukemia. Overexpression of MTGR1 can stimulate AML1-MTG8 to induce GCSF-dependent proliferation of L-G cells and to interfere with AML1-dependent transcription. AML1/MTG8 functions as a complex with MTGR1 and that the complex might be important in promoting leukemogenesis.
Synonyms	EHT, MTGR1, MTG8-like protein, MTG8-related protein 1
Reference Data
Protein Families	Transcription Factors

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