PPP2R2B Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Immunoblotting: 1/500-1/1,000.
Reactivity	Bovine, Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Purified peptide conjugated to KLH corresponding to the sequence NH2-Cys-Gly-Glu-Glu-Asp-Ile-Asp-THr-Arg-Lys-Ile-Asn-Asn-Ser-Phe-COOH. This peptide antibody corresponds to N-terminal peptide of PP2A/Bb regulatory subunit having a MW of 53kDa. The sequence used is amino acid 2-14.
Specificity	This antibody reacts to serine/threonine protein phosphatase 2A/B beta. Minimal cross reactivity against 2A/Bg .
Isotype	IgG
Formulation	PBS with 0.08% Sodium Azide as preservative. State: Purified State: Liquid purified Ig (0.2µm sterile filtered)
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	protein phosphatase 2 regulatory subunit Bbeta
Database Link	Entrez Gene 60660 RatEntrez Gene 72930 MouseEntrez Gene 5521 Human UniProt ID Q00005
Background	PPP2R2B belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This protein is a beta isoform of the regulatory subunit B55 subfamily.
Synonyms	PP2A subunit B B-beta isoform, B55-beta isoform, PR55-beta isoform, R2-beta isoform, protein phosphatase 2A 55 kDa regulatory subunit B beta
Reference Data
Protein Families	Druggable Genome, Phosphatase
Protein Pathways	Tight junction

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