KDELR3 Rabbit Polyclonal Antibody

CAT#: AP01401PU-N

KDELR3 rabbit polyclonal antibody, Aff - Purified



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CNY 4,640.00


货期*
2周

规格
    • 100 ug

Product images

Specifications

Product Data
Applications IHC, WB
Recommend Dilution Western Blot: 1/500-1/1000.
Immunohistochemistry on paraffin sections: 1/50-1/200.
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Specificity KDEL Receptor 3 antibody detects endogenous levels of KDEL Receptor 3 protein. (region surrounding Leu95)
Formulation Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration 1.0 mg/ml
Purification Affinity chromatography
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Predicted Protein Size ~ 28 kDa
Gene Name KDEL endoplasmic reticulum protein retention receptor 3
Background Soluble proteins in the endoplasmic reticulum (ER) contain a specific carboxy terminal sequence KDEL (Lys-Asp-Glu-Leu), and include the coat proteins required for vesicle budding from the ER, proteins that form retrogradevesicles on post-ER compartments, and integral membrane proteins that target vesicles to their correct destination. The retention of these soluble proteins in the ER depends on the interaction of the KDEL sequence with the corresponding KDEL receptor, also designated ERD2, in the Golgi apparatus.When KDEL proteins reach the Golgi complex, they are recognized by the KDEL receptor and transported retrograde in COPI-coated vesicles back to the ER. The small GTPase ADP-ribosylation factor 1 (ARF1), a regulator of vesicle transport, interacts with the KDEL receptor.
Synonyms ERD2L3
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Vibrio cholerae infection
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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