KAT2A Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western Blot: 1/500-1/1000. Immunohistochemistry on paraffin sections: 1/50-1/200.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 400-448 of Human AP-2γ.
Specificity	This antibody detects endogenous levels of GCN5 protein.
Formulation	Phosphate buffered saline (PBS), pH~7.2 State: Aff - Purified State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE). Preservative: 0.05% Sodium Azide
Concentration	1.0 mg/ml
Purification	Affinity Chromatography using epitope-specific immunogen.
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	~45 kDa
Gene Name	lysine acetyltransferase 2A
Database Link	Entrez Gene 2648 Human UniProt ID Q92830
Background	KAT2A / GCN5 is a transcriptional co-activator that has histone acetyltransferase activity. It exhibits significant histone acetyltransferase activity with core histones but not with nucleosome core particles. KAT2A is a component of the TFTC-HAT and STAGA complexes. KAT2A is also recruited by the viral protein Tat during HIV infection, inducing chromatin remodelling of proviral genes.
Synonyms	Histone acetyltransferase KAT2A, Histone acetyltransferase GCN5, HsGCN5, HGCN5, Lysine acetyltransferase 2A, STAF97
Reference Data

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