Botulinum neurotoxin type E Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	Dot Blot. ELISA. Western Blot.
Reactivity	Clostridium botulinum
Host	Rabbit
Clonality	Polyclonal
Immunogen	Type E Neurotoxin and complexing Proteins
Specificity	This antibody reacts to C. botulinum Type E Neurotoxin Complex, neurotoxin or protein isolates.
Formulation	1X PBS, pH 7.2 containing 20% glycerol State: Purified State: Liquid purified IgG
Concentration	lot specific
Purification	Protein G Sepharose chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Database Link	UniProt ID Q00496
Background	Clostridium botulinum E Toxoid acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase. It has a non-toxic component which is necessary to maintain toxicity.
Synonyms	Clostridium Botulinum Toxin E, BoNT/E, Bontoxilysin-E
Note	Centrifuge before opening to ensure complete recovery of vial contents.
Reference Data

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