Neuroligin 4 (782-945, Intracell. Dom.) Mouse Monoclonal Antibody [Clone ID: S98-7]

Specifications

Product Data
Clone Name	S98-7
Applications	IF, WB
Recommend Dilution	Western blot: 1/1000; 1 μg/ml was sufficient for detection of Neuroligin-4 in 20 μg of mouse brain lysate by colorimetric immunoblot analysis using HRP conjugated secondary antibody. Immunocytochemistry.
Reactivity	Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Fusion protein amino acids 782-945 (intracellular, C-terminus) of mouse Neuroligin 4.
Specificity	This antibody detects Neuroligin 4; ~125-130 kDa. ( ~45% identity with Neuroligin-1, -2 and -3)
Isotype	IgG1
Formulation	PBS pH 7.4, 50% Glycerol, 0.09% Sodium azide State: Purified State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Protein G chromatography
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Database Link	UniProt ID B0F2B4
Background	The Nlgn4l gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs, large (Drosophila) homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Two transcript variants encoding the same protein have been identified for this gene.
Synonyms	Neuroligin-4*, Neuroligin 4-like, NL-4, Nlgn4l, Nlgn4, Nlgn4x
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.