CAPNS1 Mouse Monoclonal Antibody [Clone ID: AT1D11]

Specifications

Product Data
Clone Name	AT1D11
Applications	ELISA, FC, ICC/IF, IF, WB
Recommend Dilution	The antibody has been tested by ELISA, Western blot analysis, ICC/IF and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human CAPNS1 (84-268aa) purified from E. coli
Isotype	IgG1, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	calpain small subunit 1
Database Link	NP_001740 Entrez Gene 826 Human UniProt ID P04632
Background	CAPNS1, also known as Calpain small subunit 1, are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. Two transcript variants encoding the same protein have been identified for this gene.
Synonyms	Calpain small subunit 1, Calpain, small subunit 1, 30K, CALPAIN4, CANP, CANPS, CAPN4, CDPS, CSS1
Reference Data
Protein Families	Druggable Genome, Protease

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