Cathepsin Z (CTSZ) Mouse Monoclonal Antibody [Clone ID: AT6G11]

Specifications

Product Data
Clone Name	AT6G11
Applications	ELISA, ICC/IF, WB
Recommend Dilution	The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human CTSZ (62-303aa) purified from E. coli
Isotype	IgG2b, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	cathepsin Z
Database Link	NP_001327 Entrez Gene 1522 Human UniProt ID Q9UBR2
Background	CTSZ (Cathepsin Z), also known as Cathepsin X and Cathepsin P, is 303 amino acid protein. It is lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity. This gene is widely expressed in cancer cell lines, primary tumors. CTSZ may be involved in tumor progression. And, CTSZ plays a role in normal intracellular protein degradation
Synonyms	Carboxypeptidase LB, Cathepsin B2, Cathepsin IV, Cathepsin P, Cathepsin X, Cathepsin Y, Cathepsin Z, Cathepsin Z preproprotein, Cathepsin Z1, CatX, CTSP, CTSX, CTSZ, Cysteine-type carboxypeptidase, Lysosomal carboxypeptidase B
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Lysosome

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