COTL1 Mouse Monoclonal Antibody [Clone ID: AT1D6]

Specifications

Product Data
Clone Name	AT1D6
Applications	ELISA, FACS, WB
Recommend Dilution	ELISA. Western blot. Recommended Starting Dilutions: 1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human COTL1 (1-142aa) purified from E. coli
Specificity	This antibody recognizes Human COTL1 (coactosin-like 1). Other species not tested.
Isotype	IgG2b, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	coactosin like F-actin binding protein 1
Database Link	NP_066972 Entrez Gene 23406 Human UniProt ID Q14019
Background	COTL1 (coactosin-like 1), also known as CLP, is a 142 amino acid cytoplasmic and cytoskeletal protein that belongs to the actin-binding proteins ADF family and coactosin subfamily. COTL1 is first identified in slime mold and is found at highest levels in kidney, placenta, lung and peripheral blood leukocytes. COTL1 is one of many proteins that participate in regulation of Actin's cytoskeleton through a calcium dependent mechanism, but has not been shown to have a direct effect on Actin depolymerization.
Synonyms	Coactosin like F-actin binding protein 1, Coactosin-like 1 (Dictyostelium), Coactosin-like F-actin binding protein 1, CLP
Reference Data

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