MEMO1 Mouse Monoclonal Antibody [Clone ID: AT1E9]

Specifications

Product Data
Clone Name	AT1E9
Applications	ELISA, FACS, WB
Recommend Dilution	ELISA. Western blot: 1/3000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human MEMO1 (1-297aa) purified from E. coli
Isotype	IgG1, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	mediator of cell motility 1
Database Link	NP_057039 Entrez Gene 51072 Human UniProt ID Q9Y316
Background	MEMO1 (Mediator of ErbB2-driven cell motility 1) is a 297 amino acid protein. It is thought to relax extracellular chemotactic signals that are targeted at the microtubule cytoskeleton, thereby controlling cell migration. Additionally, MEMO1 is required for breast carcinoma migration, suggesting an important role in tumorigenesis. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity.
Synonyms	Protein MEMO1, C2orf4, CGI-27, MEMO, NS5ATP7
Reference Data

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