T Cell Receptor (TCR) V beta 16 Mouse Monoclonal Antibody [Clone ID: HIS42]

Specifications

Product Data
Clone Name	HIS42
Applications	IF, IHC, IP
Recommend Dilution	Flow Cytometry. Immunofluorescence. Immunohistochemistry on Frozen Sections. Immunoprecipitation.
Reactivity	Rat
Host	Mouse
Clonality	Monoclonal
Specificity	The antibody reacts with Vbeta16 T-cell receptor; it recognizes subpopulations of peripheral CD4+ T cells and CD8+ T cells, intestinal lymphocytes and thymocytes. HIS42 monoclonal antibody induces IL-2 dependent T cell mitogenesis.
Isotype	IgG2b
Formulation	State: Supernatant State: Liquid Cell Culture Supernatant Stabilizer: 8% (v/v) FBS Preservative: 0.09% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C.
Background	The subpopulation of HIS 42 positive T cells contains both CD4 and CD8 positive cells, in the same ratio as found in the peripheral T cell population. When bound to Sepharose beads, HIS 42 induces T cell proliferation in the presence of IL-2. In contrast to lymph node T cells a number of thymocytes are found to express HIS 42 only in the cytoplasm or together with membrane expression. Most bright HIS 42 surface labelled thymocytes are also positive for MRC OX-44, a marker predominantly identifying mature thymocytes.
Synonyms	TCR V beta-16, TCR Vb16
Reference Data

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