Human Kappa Light Chain Mouse Monoclonal Antibody [Clone ID: 2B7]

Specifications

Product Data
Clone Name	2B7
Applications	IHC
Recommend Dilution	Immunohistochemistry on Frozen Sections: 1/50 preferably in PBS. Immunohistochemistry on Paraffin Sections.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	The antibody reacts with free Kappa chains, but not with Kappa chains attached to heavy chains. No reaction is observed with Ig Kappa on membranes of lymphocytes. No crossreactivity with Lambda chains. In Ouchterlony Immunodiffusion no reaction with Bence Jones Kappa is observed. The antibody reacts with Kappa chain containing cells in sections from sublimate fixed and paraffin embedded tissues. All cytoplasmic Ig Kappa containing cells from bone marrow cells recognized by conventional anti kappa antibodies will be recognized by these monoclonal antibodies.
Isotype	IgG2b
Formulation	PBS State: Supernatant State: Liquid Supernatant Stabilizer: 1% BSA Preservative: 10mM Sodium Azide, 1% FCS
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Background	Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda; both having a molecular weight of 22.5kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.
Reference Data

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