Havcr2 Rat Monoclonal Antibody [Clone ID: 25F.1D6]

Specifications

Product Data
Clone Name	25F.1D6
Applications	FC, IHC
Recommend Dilution	Immunohistochemistry. Flow Cytometry.
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Specificity	This monoclonal antibody reacts with Mouse Tim-3 type 1 transmembrane protein. Other species not tested.
Isotype	IgG2a
Formulation	PBS State: Purified State: Liquid purified IgG fraction from Ascites Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	hepatitis A virus cellular receptor 2
Database Link	Entrez Gene 171285 Mouse UniProt ID Q8VIM0
Background	This 281 amino acid type 1 transmembrane protein contains an immunoglobulin and mucin-like domain in its extra-cellular portion and a tyrosine phosphorylation motif in its cytoplasmic portion. Tim-3 is a member of the immunoglobulin super-family and is expressed on Th1 lymphocytes and CD11b+ macrophages. Tim-3 is a T helper type 1 (TH1)-specific molecule that regulates TH1 mediated auto and alloimmune responses and the induction of peripheral immunological tolerance.
Synonyms	TIMD-3, TIM3, TIM-3, T-cell membrane protein 3, HAVCR-2
Reference Data

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