FADS1 Mouse Monoclonal Antibody [Clone ID: 2D9]

Specifications

Product Data
Clone Name	2D9
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Immunohistochemistry on Paraffin Sections: 5 µg/ml. Western Blot: 1/500 - 1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	FADS1 antibody was raised against (NP_037534, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity	This antibody reacts to FADS1.
Isotype	IgG2a
Formulation	PBS, pH 7.2 State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	fatty acid desaturase 1
Database Link	Entrez Gene 3992 Human UniProt ID O60427
Background	FADS1 is a component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA)(20:5n-3) respectively.
Synonyms	FADS-1, FADSD5, Fatty acid desaturase 1, Delta(5) fatty acid desaturase, Delta(5) desaturase, D5D
Reference Data
Protein Families	Transcription Factors, Transmembrane
Protein Pathways	Biosynthesis of unsaturated fatty acids

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