IL9R Mouse Monoclonal Antibody [Clone ID: AH9R7]
CAT#: AM26785PU-N
IL9R mouse monoclonal antibody, clone AH9R7, Purified
Conjugation: PE
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CNY 3140.00
货期*
5周
规格
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Specifications
| Product Data | |
| Clone Name | AH9R7 |
| Applications | ELISA, FC |
| Recommend Dilution | Flow cytometry: 1-5 μg/ml. It is recommended to use bright fluorochromes or signal multiplying detection. ELISA. |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Immunogen | Human CD129-transfected cell line |
| Specificity | This antibody recognizes CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. |
| Isotype | IgG2b |
| Formulation | Phosphate buffered saline (PBS) State: Purified State: Liquid Ig fraction Preservative: 15 mM sodium azide, approx. pH 7.4 |
| Concentration | lot specific |
| Purification | Protein-A affinity chromatography (> 95% pure by SDS-PAGE) |
| Conjugation | Unconjugated |
| Storage Condition | Store undiluted at 2-8°C. DO NOT FREEZE! |
| Gene Name | interleukin 9 receptor |
| Database Link | |
| Background | CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma. |
| Synonyms | Interleukin-9 receptor, IL-9R, IL-9 receptor |
| Reference Data | |
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