CD300E Mouse Monoclonal Antibody [Clone ID: UP-H2]

Specifications

Product Data
Clone Name	UP-H2
Applications	FC
Recommend Dilution	Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	CD300e-HA-transfected cells
Specificity	This antibody recognizes CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.
Isotype	IgG1
Formulation	Phosphate buffered saline (PBS) Label: PE State: Liquid purified Ig fraction Stabilizer: Phosphate buffered saline (PBS) Preservative: Containing 15 mM sodium azide Label: Conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
Conjugation	PE
Storage Condition	Store undiluted at 2-8°C. Do not freeze! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Gene Name	CD300e molecule
Database Link	Entrez Gene 342510 Human UniProt ID Q496F6
Background	CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.
Synonyms	CLM-2, CD300LE, CLM2, IREM2, CMRF35-A5
Reference Data

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