LCN2 Mouse Monoclonal Antibody [Clone ID: 697]

Specifications

Product Data
Clone Name	697
Applications	ELISA, IF
Recommend Dilution	Immunoassay. Immunofluorescence: The typical starting working dilution is 1/50.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	The monoclonal antibody 697 reacts with Human neutrophil lipocalin (HNL), also known as Human nGAL (25 kDa).
Isotype	IgG1
Formulation	PBS State: Purified State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 0.1% BSA Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Protein G Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C.
Gene Name	lipocalin 2
Database Link	Entrez Gene 3934 Human UniProt ID P80188
Background	Lipocalins are a widespread family of small, robust proteins that typically transport or store biological compounds which are either of low solubility or are chemically sensitive, including vitamins, steroids, odorants and metabolic products. The members of this lipocalins share a high similarity in their tertiary structures in spite of a low degree in amino-acid sequence identity: three highly conserved sequence motifs form a funnel-like beta barrel which encloses a hydrophobic pocket for the internal ligand binding. The human neutrophil lipocalin (HNL) is produced by neutrophil leukocytes and stored in intracellular specific granules. Neutrophil lipocalin is covalently linked to gelatinase B (MMP-9) and proMMP is stored in three forms: the monomeric form (92 kDa), the homodimer (220 kDa) and a heterodimer (125 kDa). During inflammation and neoplastic transformation the human neutrophil lipocalin (HNL) is produced in neutrophils and in epithelial cells. Furthermore neutrophil lipocalin is a superior means to distinguish acute bacterial and viral infections as well as it enables the determination of the neutrophil activation level.
Synonyms	LCN2, HNL, NGAL, p25, Oncogene 24p3
Reference Data

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