HLA Class II DR Mouse Monoclonal Antibody [Clone ID: EDU-1]

Specifications

Product Data
Clone Name	EDU-1
Applications	FC, IHC
Recommend Dilution	Immunohistochemistry on frozen sections: ≤0.1μg/ml (1:2000). Has been described to work in FACS.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody recognizes the HLA DR antigen, an HLA class II antigen with homology to murine H-2E.
Isotype	IgG2b
Formulation	Phosphate buffered saline pH 7.2 (PBS), 5mg/ml bovine serum albumin (BSA), and 0.09% sodium azide as a preservative. State: Aff - Purified State: Lyophilized Ig fraction
Reconstitution Method	Reconstitute by adding 0.5ml distilled water.
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Background	HLA-DR is an αβ heterodimer. The N-terminal domain of the mature protein forms an alpha-helix that constitutes the exposed part of the binding groove, the C-terminal cytoplasmic region interacts with the other chain forming a beta-sheet under the binding groove spanning to the cell membrane.
Synonyms	HLA-DR, HLA class II histocompatibility antigen DR, MHC class II antigen DR
Note	Antigen distribution: Isolated cells: Antigen presenting cells (macrophages, Bcells and dendritic cells) are the cells in which DR are typically found.
Reference Data

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