CD24 Mouse Monoclonal Antibody [Clone ID: 32D12]

Specifications

Product Data
Clone Name	32D12
Applications	FC, IHC
Recommend Dilution	Immunohistochemistry on frozen sections: 1 μg/ml (1:200). Has been described to work in FACS. Suggested positive control: Human tonsil.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody detects CD24.
Isotype	IgG1
Formulation	Stock solution contains 0.2mg/ml IgG, phosphate buffered saline pH 7.2 (PBS), 5mg/ml bovine serum albumin (BSA), and 0.09% sodium azide as a preservative. State: Aff - Purified State: Lyophilized Ig fraction
Reconstitution Method	Reconstitute by adding 0.5ml distilled water.
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	CD24 molecule
Database Link	Entrez Gene 100133941 Human UniProt ID P25063
Background	CD24 antigen is expressed throughout Bcell development and is downregulated as bone marrow progenitors mature. CD24 expression is lost when human B-cells become plasma cells. The cellular function for human CD24 is unknown so far. Diagnostically, it can serve as a marker for staging B-cell development, and it is expressed at high levels in small cell lung carcinoma. CD24 is a member of a family that also includes Heat Stable Antigen HSA and CD52. It is a glycosylphosphatidylinositol (GPI) anchored glycoprotein.
Synonyms	X62 heat stable antigen, HSA
Note	Molecular weight of antigen: 35 - 45 kD. Antigen distribution: Isolated cells: granulocytes. Tissue sections: B-cells (germinal centers weak); follicular dendritic cells; variety of epithelial cell types.
Reference Data

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