Cd9 Rat Monoclonal Antibody [Clone ID: EM-04]

Specifications

Product Data
Clone Name	EM-04
Applications	FC, IF, IP, WB
Recommend Dilution	Flow Cytometry: 4 μg/ml. Immunoprecipitation. Western blot: 1 μg/ml (non-reducing conditions). Immunocytochemistry.
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Immunogen	Permeabilized murine bone marrow-derived mast cells (BMMC)
Specificity	This antibody recognizes CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.
Isotype	IgG1
Formulation	Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 State: Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Purified by protein-G affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	CD9 antigen
Database Link	Entrez Gene 12527 Mouse UniProt ID P40240
Background	CD9 belongs to proteins of tetraspanin family that orchestrate cholesterol-associated tetraspanin-enriched signaling microdomains within the plasma membrane, forming complexes with each other as well as with integrins, membrane-anchored growth factors and other proteins. CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 is also considered as metastasis suppressor in solid tumors.
Synonyms	MIC3, TSPAN29, GIG2, p24, Tetraspanin-29, 5H9 antigen
Reference Data

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