gamma Adaptin (AP1G1) Mouse Monoclonal Antibody [Clone ID: IMD-113]

Specifications

Product Data
Clone Name	IMD-113
Applications	WB
Recommend Dilution	Western Blot: 2 - 4 μg/ml.
Reactivity	Human, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	AP-1 adaptor from bovine brain.
Specificity	This antibody reacts to AP1 complex subunit gamma-1.
Isotype	IgG2b
Formulation	1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative. State: Purified State: Lyphilized purified Ig fraction
Reconstitution Method	Restore with 1.2% sodium acetate or neutral PBS
Concentration	0,1 mg/ml (after reconstitution with PBS)
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	adaptor related protein complex 1 gamma 1 subunit
Database Link	Entrez Gene 171494 RatEntrez Gene 164 Human UniProt ID O43747
Background	Adaptins are important components of heterotetrameric adaptor complexes (APs) whose role is to promote the formation of clathrin-coated pits and vesicles. The AP-1 adaptor, localized at the trans-Golgi network, is composed of 2 approximately 100-kD subunits, beta-prime-adaptin and gamma-adaptin. The predicted 825-amino acid protein shares 99% identity with mouse gamma-adaptin. Northern blot analysis revealed that gamma-adaptin was expressed as a 7.5-kb transcript in all human tissues tested. Human gamma-adaptin gene (ADTG) is assigned to 16q23.
Synonyms	ADTG, CLAPG1, gamma 1 Adaptin, gamma Adaptin
Reference Data
Protein Pathways	Lysosome

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