Neurofilament (NEFL) Mouse Monoclonal Antibody [Clone ID: NF-68]

CAT#: AM20649PU-N

Neurofilament (NEFL) mouse monoclonal antibody, clone NF-68, Purified



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CNY 5,599.00


货期*
5周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name NF-68
Applications IHC, WB
Recommend Dilution Western Blot: 1 - 2 μg/ml.
Immunohistochemistry on frozen and paraffin embedded sections: 2 - 4 μg/ml.
Reactivity Human, Porcine, Rat
Host Mouse
Clonality Monoclonal
Immunogen Pig spinal cord.
Specificity This antibody reacts to Neurofilament L (68kDa).
Formulation 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
State: Purified
State: Lyphilized purified Ig fraction
Reconstitution Method Restore with 1.2% sodium acetate or neutral PBS
Concentration 0,1 mg/ml (after reconstitution with PBS)
Purification Affinity chromatography
Conjugation Unconjugated
Storage Condition Prior to reconstitution store at -20°C.
Following reconstitution store undiluted at 2-8°C for one month
or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name neurofilament, light polypeptide
Background Neurofilaments are composed of 3 neuron-specific proteins with apparent molecular masses of 68 Kd (NFL), 125 kD (NFM) and 200 kD (NFH) on SDS-gel electrophoresis. And they have a role in the maturation of regenerating myelinated axons. Neurofilament 68 (NF68), also called Neurofilament rotein, Light Chain (NFL). It is one of the most abundant cytoskeletal omponents of the neuron.Mutations in this gene were reported as a cause for autosomal dominant Charcot-Marie-Tooth type 2E (CMT2E) linked to chromosome 8p21. NFL was identified repeatedly in both screenings and found to interact with Myotubularin-related 2 gene, MTMR2 in both Schwann cells and neurons.
Synonyms NF-L,NEFL, NF68, 68 kDa neurofilament protein
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS
Protein Pathways Amyotrophic lateral sclerosis (ALS)
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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