Cyclin D3 (CCND3) Mouse Monoclonal Antibody [Clone ID: CY-D3]

Specifications

Product Data
Clone Name	CY-D3
Applications	IF, WB
Recommend Dilution	Western Blot: 0.25 - 0.5 μg/ml. Immunohistochemistry on frozen and paraffin sections: 0.5 - 1 μg/ml. Immunocytochemistry.
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human cyclin D3 protein
Specificity	This antibody reacts to Cyclin D3.
Isotype	IgG1
Formulation	1.2 % sodium acetate, with 2 mg BSA and 0.2 mg sodium azide as preservative. State: Purified State: Lyphilized purified Ig fraction
Reconstitution Method	Restore with 1.2 % sodium acetate or PBS
Concentration	0,1 mg/ml (after reconstitution with PBS)
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	cyclin D3
Database Link	Entrez Gene 12445 MouseEntrez Gene 25193 RatEntrez Gene 896 Human UniProt ID P30281
Background	Three cyclin D genes are normally expressed during the G1 phase of the cell cycle. The three human D-type cyclin genes encode small (33-34 kD) proteins that share an average of 57% identity over the entire coding region and 78% in the cyclin box. Mouse cyclin D3 gene contains 5 exons spanning about 7 kb of genomic DNA. CCND3 gene is mapped to 6p21.
Synonyms	Cyclin-D3, CCND3
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Cell cycle, Focal adhesion, Jak-STAT signaling pathway, p53 signaling pathway, Wnt signaling pathway

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