Collagen III (COL3A1) Mouse Monoclonal Antibody [Clone ID: Col-29]

Specifications

Product Data
Clone Name	Col-29
Applications	IHC, WB
Recommend Dilution	Western Blot: 0.25-0.5 μg/ml. Immunohistochemistry on Frozen Sections: Use at 0.5-1 μg/ml to detect Collagen type III in Formalin/Acetone fixed tissues.
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human Collagen type III
Specificity	This antibody recognizes Collagen type III.
Isotype	IgG1
Formulation	1.2% Sodium Acetate State: Purified State: Lyophilized purified Ig fraction Stabilizer: 2 mg BSA Preservative: 0.01 mg Sodium Azide
Reconstitution Method	Restore with 1.2% Sodium Acetate or neutral PBS.
Concentration	0.1 mg/ml (after reconstitution with PBS)
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	collagen type III alpha 1 chain
Database Link	Entrez Gene 12825 MouseEntrez Gene 84032 RatEntrez Gene 1281 Human UniProt ID P02461
Background	Collagen type III, also known as COL3A1, is assigned to chromosome 2. Ultrastructural analysis of tissues from mutant mice revealed that type III collagen is essential for normal collagen I fibrillogenesis in the cardiovascular system and other organs. Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular development.
Synonyms	COL3A1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	ECM-receptor interaction, Focal adhesion

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