CD162 (SELPLG) Rat Monoclonal Antibody [Clone ID: HECA-452]

Specifications

Product Data
Clone Name	HECA-452
Applications	FC, IHC
Recommend Dilution	Flow Cytometry. Immunohistochemistry on Paraffin Sections: 10 µg/ml.
Reactivity	Human, Mouse
Host	Rat
Clonality	Monoclonal
Immunogen	SELPLG / PSGL-1 / CD162 antibody was raised against stromal preparation from human tonsils
Specificity	This antibody reacts to Selectin P Ligand (SELPLG).
Isotype	IgM
Formulation	Phosphate-buffered solution, pH 7.2, 0.09% sodium azide State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	selectin P ligand
Database Link	Entrez Gene 20345 MouseEntrez Gene 6404 Human UniProt ID Q14242
Background	SELPLG is the high affinity counter-receptor for P-selectin on myeloid cells and stimulated T lymphocytes. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. The organization of the SELPG gene closely resembles that of CD43 and the human platelet glycoprotein GpIb-alpha both of which have an intron in the 5-prime-noncoding region, a long second exon containing the complete coding region, and TATA-less promoters.
Synonyms	PSGL-1, Selectin P ligand, SELPLG
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Cell adhesion molecules (CAMs)

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