Integrin beta 4 (ITGB4) Rat Monoclonal Antibody [Clone ID: 439-9B]

CAT#: AM20454PU-N

Integrin beta 4 (ITGB4) rat monoclonal antibody, clone 439-9B, Purified



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AM20454PU-N is a replacement of TA320398.

CNY 5,654.00


货期*
5周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name 439-9B
Applications FC, IHC, WB
Recommend Dilution Flow Cytometry.
Immunohistochemistry on Frozen Sections.
Immunohistochemistry on Paraffin Sections: 20 µg/ml.
Western Blot.
Reactivity Human
Host Rat
Clonality Monoclonal
Immunogen Human ITGB4
Specificity Recognizes Integrin Beta 4 (ITGB4).
Formulation Aqueous buffer, 0.09% Sodium Azide, may contain carrier protein/stabilizer
State: Purified
State: Liquid purified IgG fraction
Concentration lot specific
Purification Affinity Chromatography
Conjugation Unconjugated
Storage Condition Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Gene Name integrin subunit beta 4
Background Integrins are heterodimers composed of noncovalently associated transmembrane alpha and beta subunits. The 16 alpha and 8 beta subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrinmediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.
Synonyms ITGB4, GP150
Reference Data
Protein Families Druggable Genome
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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