Eph receptor B4 (EPHB4) Mouse Monoclonal Antibody [Clone ID: 67CT23.5.8]

Specifications

Product Data
Clone Name	67CT23.5.8
Applications	WB
Recommend Dilution	ELISA: 1/10000. Western blotting: 1/200-1/2000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	EPHB4 recombinant protein.
Specificity	This antibody is specific to EPHB4.
Isotype	IgG1
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	EPH receptor B4
Database Link	Entrez Gene 2050 Human UniProt ID P54760
Background	Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.
Synonyms	Ephrin type-B receptor 4, HTK, TYRO11
Reference Data

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