KLF4 Mouse Monoclonal Antibody [Clone ID: 56CT5.1.6]

Specifications

Product Data
Clone Name	56CT5.1.6
Applications	IF, WB
Recommend Dilution	ELISA: 1/1,000. Western blotting: 1/200-1/2000. Immunofluorescence.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	KLF4 recombinant protein.
Specificity	This antibody is specific to KLF4.
Isotype	IgG1
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	0.5 mg/ml
Purification	Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	Kruppel-like factor 4 (gut)
Database Link	Entrez Gene 9314 Human UniProt ID O43474
Background	Krüppel-like factor 4 (KLF4) is a transcription factor involved in both proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas and has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. KLF4 is also involved in reprogramming differentiated cells into pluripotent stem cells. KLF4 can act as a transcriptional activator or repressor, but the underlying mechanisms are poorly understood.
Synonyms	EZF, GKL
Reference Data

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