VEGFC Mouse Monoclonal Antibody [Clone ID: 30AT1174.77]

Specifications

Product Data
Clone Name	30AT1174.77
Applications	WB
Recommend Dilution	ELISA: 1/1,000 Western blotting: 1/100-1/500.
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	This monoclonal antibody is generated from mice immunized with three KLH conjugated synthetic peptides selected from the N-terminal, central, and C-terminal regions of human VEGF3.
Specificity	This antibody is specific to VEGFC.
Isotype	IgG1
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	vascular endothelial growth factor C
Database Link	Entrez Gene 7424 Human UniProt ID P49767
Background	VEGF-C (VEGF3) is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.
Synonyms	VEGFC, VRP, Vascular endothelial growth factor C, Vascular endothelial growth factor-related protein, Flt4 ligand
Reference Data

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