Bad pSer155/118 Mouse Monoclonal Antibody [Clone ID: 27AT381]

Specifications

Product Data
Clone Name	27AT381
Applications	WB
Recommend Dilution	ELISA: 1/1,000. Western blotting1: 1/100-1/500.
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	This monoclonal antibody is generated from mice immunized with a KLH conjugated synthetic peptide corresponding to sequences in Ser155 region of mouse Bad and residue Ser155 is phosphorylated.
Specificity	This antibody is specific to mBad pSer155.
Isotype	IgG1
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	BCL2-associated agonist of cell death
Database Link	Entrez Gene 12015 Mouse UniProt ID Q61337
Background	Apoptosis is a critical aspect of cellular function and is implicated in a broad range of human diseases, from cancer to neurodegenerative and cardiovascular diseases. Intrafamilial Bcl-2 protein contacts are thought to regulate key aspects of apoptosis. The corruption of apoptotic instructions is associated with a large subset of human diseases, ranging from cancer and cardiovascular disease to neurodegenerative diseases, and name just a few. Understanding regulation of apoptosis is necessary to constructing a strategy for pharmaceutical intervention. The BH3 domain of Bcl-2 family members has been identified as key to the Bcl-2 regulatory function, although details are not fully elucidated.
Synonyms	BAD, BBC6, BCL2L8, Bcl-2-like protein 8, Bcl2-L-8
Reference Data

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