NANS Mouse Monoclonal Antibody [Clone ID: AT1G6]

Specifications

Product Data
Clone Name	AT1G6
Applications	ELISA, ICC/IF, WB
Recommend Dilution	ELISA. Western blot (recommended dilution 1:1000).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human NANS (1-359aa) purified from E. coli
Specificity	The antibody recognizes human NANS. Other species not tested.
Isotype	IgG1, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	N-acetylneuraminate synthase
Database Link	NP_061819 Entrez Gene 54187 Human UniProt ID Q9NR45
Background	NANS (Sialic acids synthease) is an enzyme that functions in the biosynthetic pathways of sialic acids. Expressed ubiquitously, NANS enzymatically catalyzes the H2O-dependent formation of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), both of which are sialic acids. NANS uses N-acetylmannosamine 6-phosphate as a substrate for Neu5Ac synthesis and mannose 6-phosphate as a substrate for KDN synthesis.
Synonyms	Sialic acid synthase, SAS, N acetylneuraminate synthase
Reference Data
Protein Pathways	Amino sugar and nucleotide sugar metabolism, Metabolic pathways

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