Sumo 2 (SUMO2) Mouse Monoclonal Antibody [Clone ID: AT10F1]

Specifications

Product Data
Clone Name	AT10F1
Applications	ELISA, FACS, ICC/IF, IF, IHC, WB
Recommend Dilution	ELISA. Western blot (~1/1000). Immunofluorescence (1/250-1/500). Immunohistochemistry on Paraffin embedded tissues (1/50). Flow Cytometry (~5 µg in 106 cells).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human SUMO2 (1-93aa) purified from E.coli
Specificity	The antibody recognizes Human SUMO2/3. Other species not tested.
Isotype	IgG2b, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	small ubiquitin-like modifier 2
Database Link	NP_008868 Entrez Gene 6613 Human UniProt ID P61956
Background	SUMO (small ubiquitin-related modifier) is the best-characterized member of a growing family of ubiquitin-related proteins. 8-11 kDa that covalently modify various intracellular proteins. It resembles ubiquitin in its structure, its ability to be ligated to other proteins. SUMO regulates cellular function of a variety of target proteins. SUMO proteins are expressed as their precursor forms. Cleavage of the residues after the GG region of these precursors by SUMO-specific proteases in maturation is a prerequisite for subsequent sumoylation. Notably, SUMO2 and SUMO3 precursors have 96% sequence identity, and recent studies have shown protein substrates conjugated with SUMO2 or SUMO3 have similar, if not identical, biological consequences.
Synonyms	ubiquitin like protein SMT3B.Small ubiquitin-related modifier 3, SuMO3, SuMO2, SMT3H2, SMT3H1, SMT3B, SMT3A, SMT3 suppressor of mif two 3 homolog 2, SMT3 homolog 2, SMT 3B, Small ubiquitin-related modifier 2 SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae), Small ubiquitin related modifier 2, Small ubiquitin like modifier 2, Sentrin2, MGC117191, HSMT3
Reference Data
Protein Families	Druggable Genome

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