IL32 (1-131) Mouse Monoclonal Antibody [Clone ID: AT2F9]

Specifications

Product Data
Clone Name	AT2F9
Applications	ELISA, ICC/IF, IF, WB
Recommend Dilution	ELISA. Western blot (1:500 - 1:1000). Immnocytochemistry / Immunoflourescence.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human IL32 (1-131aa) purified from E. coli
Specificity	The antibody recognizes human IL-32 at aa1-131. Other species not tested.
Isotype	IgG1, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	interleukin 32
Database Link	NP_001012651 Entrez Gene 9235 Human UniProt ID P24001
Background	The gene encoding IL32 is located on human chromosome 16p13. 3 and is organized into eight exons. IL32 is mainly expressed in natural killer cells, T cells, epithelial cells, and blood monocytes. It can induce the proinflammatory cytokines TNFalpha and IL1beta in murine peritoneal macrophages as well as in phorbol ester-differentiated human THP1 cells. In the inflamed lesions of chronic pancreas, the ductal expression of IL32 was markedly increased. Pancreatic duct cells are the local source of IL32, and IL32 may play an important role in inflammatory responses and pancreatic cancer growth. Recently, a synergism between IL32 and other well characterized players in innate immunity has been documented.
Synonyms	Interleukin 32, Natural killer cells protein 4, Natural killer cell transcript 4, NK4, Tumor necrosis factor alpha-inducing factor, TAIF, TAIFb, TAIFd
Reference Data
Protein Families	Secreted Protein

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