FUS2 (NAT6) Mouse Monoclonal Antibody [Clone ID: AT2F4]

Specifications

Product Data
Clone Name	AT2F4
Applications	ELISA, FACS, ICC/IF, IF, WB
Recommend Dilution	ELISA. Western blot (1:500 - 1:1,000). Immunofluorescence (1:500 - 1:1,000).
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant FUS2 (1-308aa) purified from E. coli
Specificity	The antibody recognizes human and mouse (Western blot) NAT6 (FUS2). Other species not tested.
Isotype	IgG1, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	N-acetyltransferase 6
Database Link	NP_036323 Entrez Gene 24142 Human UniProt ID Q93015
Background	Vertebrate FUS2 genes, which are known to be putative tumor suppressor gene, contain several important domains such as the catalytic N-acetyltransferase (NAT) domain. NAT domain is essential enzymes involved in several sophisticated cellular processes such as N-acetylation, O-acetylatin. NAT enzymes may be involved in susceptibility to cancer including colorectal cancer because of the presence of carcinogenic heterocyclic amines in some cooked foods. FUS2 was physically localized to the cytoplasm. Also, FUS2 showed the actin dependent movement, closely related to the polarization in the budding yeast, Saccharomyces cerevisiae.
Synonyms	Protein fus 2, Protein fusion-2, FuS-2, NAT6, N acetyltransferase 6
Reference Data
Protein Pathways	Glycerophospholipid metabolism, Limonene and pinene degradation, Phenylalanine metabolism, Tyrosine metabolism

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