CRABP1 Mouse Monoclonal Antibody [Clone ID: AT1A1]

Specifications

Product Data
Clone Name	AT1A1
Applications	ELISA, FACS, ICC/IF, IHC, WB
Recommend Dilution	ELISA. Western blot: 1/500-1/1,000. Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human CRABP1 (1-137aa) purified from E. coli
Specificity	The antibody recognizes Human and Mouse CRABP1. Other species not tested.
Isotype	IgG2b, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	cellular retinoic acid binding protein 1
Database Link	NP_004369 Entrez Gene 12903 MouseEntrez Gene 1381 Human UniProt ID P29762
Background	CRABP1 (cellular retinoic acid-binding protein 1) is a member of specific carrier proteins for members of the vitamin A family. CRABP1 is assumed to play an important role in retinoic acid-mediated differentiation and proliferation processes. CRABP1 is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid. It is constitutively expressed and is believed to have different functions in the cell than the related CRABP2. Interestingly, Sytenol A bakuchiol has very specific receptor specificity over retinol and has no effect on the RAR-beta and RAR-gamma receptors and down-regulates CRABP1.
Synonyms	Cellular retinoic acid binding protein 1, CRABP, CRABP-I, CRABPI, RBP5, Cellular retinoic acid binding protein 1 CRABP 1, CRABP I, RBP 5, Retinoic acid binding protein I cellular
Reference Data

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