Glucose 6 Phosphate Dehydrogenase (G6PD) (35-506) Mouse Monoclonal Antibody [Clone ID: AT2F6]

Specifications

Product Data
Clone Name	AT2F6
Applications	ELISA, FC, ICC/IF, IF, IHC, WB
Recommend Dilution	ELISA. Western blot (1:1,000 - 1:2,000). Immunohistochemistry on Paraffin sections (5 µg/ml). Immunocytochemistry / Immunoflourescence. Flow cytometry.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human G6PD (35-506aa) purified from E. coli
Specificity	The antibody recognizes human G6PD at aa 35-506. Other species not tested.
Isotype	IgG2b, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	glucose-6-phosphate dehydrogenase
Database Link	NP_001035810.1 Entrez Gene 2539 Human UniProt ID P11413
Background	Glucose-6-phosphate dehydrogenase (G6PD) is the rate-limiting enzyme of the pentose phosphate pathway, a metabolic pathway that supplies reducing energy to cells by maintaining the level of NADPH. G6PD converts glucose-6-phosphate into 6-phosphoglucono-delta-lactone and simultaneously produce NADPH. The NADPH in turn maintains the level of glutathione in these cells that helps protect the red blood cells against oxidative damage. G6PD deficiency cause acute hemolytic anemia.
Synonyms	glucose-6-phosphate 1-dehydrogenase, G6PD1, G6PDH
Reference Data

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