LITAF Mouse Monoclonal Antibody [Clone ID: AT5C10]

Specifications

Product Data
Clone Name	AT1F9
Applications	ELISA, FC, ICC/IF, WB
Recommend Dilution	ELISA. Western blot (1/2000-1/3000). Flow CYtometry.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human LITAF (1-161aa) purified from E. coli
Specificity	The antibody recognizes Human LITAF. Other species not tested.
Isotype	IgG2b, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	lipopolysaccharide induced TNF factor
Database Link	NP_004853 Entrez Gene 9516 Human UniProt ID Q99732
Background	Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LITAF) mediates the expression of inflammatory cytokines such as TNF-alpha in Lipopolysaccharide-induced processes. LITAF binds to STAT6B, a member of the STAT6 family forming a complex on the TNF-alpha promoter that modulates TNF activity. High levels of expression of LITAF mRNA have been observed predominantly in the placenta, peripheral blood leukocytes, lymph nodes and spleen.
Synonyms	lipopolysaccharide-induced TNF factor, PIG7, SIMPLE, FLJ38636, TP53I7
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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