LANA ORF73 (122-329) Mouse Monoclonal Antibody [Clone ID: AT4C11]

Specifications

Product Data
Clone Name	AT4C11
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western blot (1/1000-1/2000). Immunohistochemistry on Paraffin Embedded Sections (1/50-1/100).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human ORF73/HHV8 (122-329aa) purified from E. coli
Specificity	The antibody recognizes the ORF73 protein of Human herpesvirus 8 (HHV-8). Other species not tested.
Isotype	IgG2a, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Database Link	AAB62657 Entrez Gene 4961527 UniProt ID O40947
Background	ORF73 protein of human herpesvirus 8 (HHV-8) is a kaposi's sarcoma-associated herpesvirus (kSHV) latent protein which has been suspected of playing a crucial role in modulating viral and cellular gene expression. ORF73 is associated with cellular chromatin and stays on the chromosomes during cell division. It maintains the viral genomes during cell division by tethering the viral episomes to the chromosomes. It binds directly to replication origin recognition complexes (ORCs) that are primarily associated with the terminal repeat (TR) region of the HHV-8 genome.
Synonyms	Human herpesvirus 8 ORF73, Kaposi's sarcoma-associated herpesvirus
Reference Data

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