DACT3 Mouse Monoclonal Antibody [Clone ID: 2A5]

Specifications

Product Data
Clone Name	2A5
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western blot (1:250 - 500) . Immunohistochemistry on Paraffin embedded tissues (1:50).
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human DACT3 (89-202aa) purified from E. coli
Specificity	The antibody recognizes human and mouse DACT3. Other species not tested.
Isotype	IgG1, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	dishevelled binding antagonist of beta catenin 3
Database Link	NP_659493 Entrez Gene 629378 MouseEntrez Gene 147906 Human UniProt ID Q96B18
Background	DACT3, a member of the DACT (Dpr/Frodo) gene family, plays an important role in a negative regulator of Wnt/-catenin signaling. Unlike other Wnt signaling inhibitors that are silenced by DNA methylation, DACT3 repression is associated with bivalent histone modifications.
Synonyms	Thymus expressed gene 3-like, Dapper antagonist of beta-catenin homolog 3 (Xenopus laevis), Arginine rich region 1, MGC15476
Reference Data

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