AVEN Mouse Monoclonal Antibody [Clone ID: 3G4]

Specifications

Product Data
Clone Name	3G4
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western blot (1:1,000 - 1:3,000). Immunohistochemistry on paraffin sections (1:50 - 1:100).
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human PDCD12 (254-362aa) purified from E. coli
Specificity	The antibody recognizes AVEN / PDCD12.
Isotype	IgG2a, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	apoptosis and caspase activation inhibitor
Database Link	NP_065104 Entrez Gene 57099 Human UniProt ID Q9NQS1
Background	PDCD12 (Programmed cell death 12), also referred to as AVEN, represents a new class of cell death regulator. PDCD12 is a conserved intracellular membrane protein that blocks apoptosis impeded by Apaf-1 mediated caspase activation. Bcl-2 and BAD also interact with PDCD12 to prevent apoptosis. It is expressed in a wide variety of normal tissues including heart, skeletal muscle, kidney, liver, testis, and diseases such as cancer
Synonyms	cell death regulator aven, apoptosis, caspase activation inhibitor, PDCD12, programmed cell death 12
Reference Data

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