UBE2L6 Mouse Monoclonal Antibody [Clone ID: k1H3]

Specifications

Product Data
Clone Name	k1H3
Applications	ELISA, ICC/IF, IHC, WB
Recommend Dilution	ELISA. Western blot (1:1,000 - 1:3,000), recommended starting dilution is 1:2,000. Immunohistochemistry on Paraffin embedded tissue (1:50 - 1:100).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human UBE2L6 (1-152aa) purified from E. coli
Specificity	The antibody recognizes human UBE2L6. Other species not tested.
Isotype	IgG2b, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	ubiquitin conjugating enzyme E2 L6
Database Link	NP_004214 Entrez Gene 9246 Human UniProt ID O14933
Background	Ubiquitin-conjugating enzyme E2L6 (UBE2L6), also known as UbcH8, is a member of the E2 ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination of a protein substrate requires the concerted action of 3 classes of enzymes: E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin protein ligases. The E2 ubiquitin-conjugating enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene.
Synonyms	Ubiquitin conjugating enzyme E2 L6, Ubiquitin/ISG15-conjugating enzyme E2 L6, E2 ubiquitin-conjugating enzyme L6, Retinoic acid-induced gene B protein, RIG-B, UbcH8, Ubiquitin carrier protein L6, Ubiquitin-protein ligase L6
Reference Data

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