STEAP1 Mouse Monoclonal Antibody [Clone ID: J2D2]

Specifications

Product Data
Clone Name	J2D2
Applications	ELISA, ICC/IF, IF, IHC, WB
Recommend Dilution	ELISA. Western blot: 1/1000-1/2000. Immunofluorescence: 1/100-1/300. Immunohistochemsitry on Praffin Sections: 1/50-1/100.
Reactivity	Human, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human STEAP1 (1-70aa) purified from E. coli
Specificity	The antibody recognizes STEAP1.
Isotype	IgG2b, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	six transmembrane epithelial antigen of the prostate 1
Database Link	NP_036581 Entrez Gene 26872 Human UniProt ID Q9UHE8
Background	Six-transmembrane epithelial antigen of the prostate (STEAP) is expressed predominantly in human prostate tissue and in other common malignancies including prostate, bladder, colon, and ovarian carcinomas, and in Ewings sarcoma, suggesting that it could function as an almost universal tumor antigen. Immunohistochemical analysis indicated STEAP-1 localization at cell-cell junctions of the secretory epithelium of prostate and prostate cancer cells. The favorable expression profiling of STEAP-1 in normal and cancer tissues suggested its potential use as a target for immunotherapy.
Synonyms	six transmembrane epithelial antigen of the prostate 1, six transmembrane epithelial antigen of the prostate, PRSS24
Reference Data

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