Phosphoserine phosphatase (PSPH) Mouse Monoclonal Antibody [Clone ID: 3G12]

Specifications

Product Data
Clone Name	3G12
Applications	ELISA, ICC/IF, IHC, WB
Recommend Dilution	ELISA. Western blot (1/1,000-1/2,000) Recommended Starting Dilution: 1/1,000. Immunohistochemistry on Paraffin Sections (10 µg/ml).
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human PSP (1-225aa) purified from E. coli
Specificity	The antibody recognizes Phosphoserine Phosphatase.
Isotype	IgG1, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	phosphoserine phosphatase
Database Link	NP_004568 Entrez Gene 5723 Human UniProt ID P78330
Background	Human phosphoserine phosphatase (HPSP), specific for D- and L- phosphoserine, has been identified in all human tissues. HPSP is a Mg (2+) -dependent phosphoserine phosphatase. The three dimensional structure of HPSP reveals the structural and functional role of the divalent cation in the active site of phosphatases. In particular, the complex structures reveal that the open-closed environmental change of the active site, generated by local rearrangement of the alpha-helical bundle domain, is important for the substrate recognition and hydrolysis.
Synonyms	PSPH, PSPase, PSP, Phosphoserine phosphatase Human, Phosphoserine phosphatase deficiency, Phosphoserine phosphatase, O-phosphoserine phosphohydrolase, L-3-phosphoserine phosphatase, EC 3.1.3.3
Reference Data

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