CD147 (BSG) Mouse Monoclonal Antibody [Clone ID: MEM-M6/2]

CAT#: AM08322PU-N

CD147 (BSG) mouse monoclonal antibody, clone MEM-M6/2, Purified



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CNY 5,654.00


货期*
5周

规格
    • 50 ug

Product images

Specifications

Product Data
Clone Name MEM-M6/2
Applications FC, IHC
Recommend Dilution Flow Cytometry.
Immunohistochemistry on Paraffin Sections: 10 µg/ml.
Reactivity Human, Porcine
Host Mouse
Clonality Monoclonal
Immunogen A soluble recombinant form of CD147, CD147Rg, which consists of the cDNA coding for the entire extracellular region of CD147 fused to the DNA coding for the hinge region, CH2 and CH3 domain of human IgG1
Specificity AM08322PU-N recognizes extracellular Ig domain D1 of CD147 (Neurothelin), a 50-60 kDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells; it is not expressed by resting lymphocytes.
This antibody is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.
Formulation PBS, pH 7.4 containing 15 mM Sodium Azide as preservative
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein A Chromatography
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name basigin (Ok blood group)
Background CD147 plays a pivotal role in spermatogenesis, embryo implantation, neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). CD147 may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. CD147 also seems to be a receptor for oligomannosidic glycans. In vitro, it promotes outgrowth of astrocytic processes. CD147 forms homooligomers in a cis-dependent manner on the plasma membrane. It forms a complex with MMP1 at the tumor cell surface. CD147 interacts with SLC16A1 and SLC1A3; probably a BSG dimer is associated with a monocarboxylate transporter dimer. CD147 also interacts with ATP1B2, MAG and L1CAM.
Synonyms Basigin, BSG, EMMPRIN, TCSF
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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