IL5 Rat Monoclonal Antibody [Clone ID: JES1-5A10]

Specifications

Product Data
Clone Name	JES1-5A10
Applications	ELISA
Recommend Dilution	ELISA: Useful useful as a Detection/Capture antibody in a Sandwich ELISA for quantifying human IL-5 protein levels. (Ref.1-5)
Reactivity	Human
Host	Rat
Clonality	Monoclonal
Immunogen	COS-expressed recombinant human IL-5.
Specificity	This antibody is specific to Human Interleukin-5/IL-5. (Ref.1-4)
Isotype	IgG2a
Formulation	100 mM Borate buffered saline, pH 8.2 without preservatives or amine-containing buffer salts. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	interleukin 5
Database Link	Entrez Gene 3567 Human UniProt ID P05113
Background	Human Interleukin 5 (IL5) is a cytokine produced primarily by activated T lymphocytes. It exists as an antiparallel disulfide-linked homodimeric glycoprotein with 115 amino-acid residues in each chain. Known also as EDG (eosinophil differentiating factor), functions predominantly as an eosinophilopoietic factor. Analysis of its crystal structure reveals a novel two-domain structure, with each domain showing significant homology to the cytokine fold in GM-CSF, M-CSF, IL2, IL4 and growth hormone. Human and Mouse IL5 have 70% amino acid sequence homology.
Synonyms	IL-5, B-cell differentiation factor I, Eosinophil differentiation factor, T-cell replacing factor, TRF
Reference Data

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