CD3E Mouse Monoclonal Antibody [Clone ID: PPT3]

Specifications

Product Data
Clone Name	PPT3
Applications	FC
Recommend Dilution	Flow Cytometry: ≤ 1 µg/106 cells (Ref.1).
Reactivity	Porcine
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified CD3 molecules from porcine thymus
Specificity	This antibody recognizes Porcine CD3e (Mr. 23 kDa). This Monoclonal antibody PPT3 is Mitogenic when presented to peripheral blood mononuclear cells in immobilized form (Ref.1).
Isotype	IgG1
Formulation	PBS containing 0.09% Sodium Azide as preservative. Label: Biotin State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Biotin
Storage Condition	Store undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Database Link	UniProt ID Q7YRN2
Background	CD3 epsilon, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains (designated as gamma, delta, epsilon, zeta and eta) ranging in size from 16-28 kDa. CD3 epsilon is closely associated with the T cell antigen receptor (TCR), and is present on thymocytes, CD8+ and CD4+ positive cells. The CD3 epsilon complex mediates signal transduction. It plays a major role in signaling during antigen recognition, leading to T cell activation. The TCR/CD3E complex of T lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. CD3 epsilon is expressed on all T cells of all mouse strains.
Synonyms	T3/Leu-4
Reference Data

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