Klra6 Mouse Monoclonal Antibody [Clone ID: HBF-719]

Specifications

Product Data
Clone Name	HBF-719
Applications	FC
Recommend Dilution	Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1,3)
Reactivity	Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	CHO cells transfected with the B6 allele of Ly49F. (Ref.1)
Specificity	This antibody HBF-719 reacts with the B6 allele of Ly49F. It stains ~ 11% of NK1.1+CD3- splenocytes, and 3.5% (2.5 month old) to 10.0% (11 month old) of CD8+ spleen cells from C57BL/6 mice. (Ref.1)
Isotype	IgG1
Formulation	100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	killer cell lectin-like receptor, subfamily A, member 6
Database Link	Entrez Gene 16637 Mouse UniProt ID Q60653
Background	Ly49F is a member of the lectin like homodimeric Ly49 family of cell surface receptors. (Ref.1) Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down regulated. (Ref.2) These inhibitory receptors are also expressed on a subpopulation of mouse CD8+ T cells.
Synonyms	Ly-49f, Ly49-f, Ly49F
Reference Data

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