CTCF Mouse Monoclonal Antibody [Clone ID: 1D11]

CAT#: AM06561SU-N

CTCF mouse monoclonal antibody, clone 1D11, Ascites



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CNY 5,346.00


货期*
5周

规格
    • 100 ul

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Specifications

Product Data
Clone Name 1D11
Applications ELISA, WB
Recommend Dilution ELISA: 1/10000.
Western Blot: 1/500 - 1/2000.
Reactivity Human, Monkey
Host Mouse
Clonality Monoclonal
Immunogen Purified recombinant fragment of Human CTCF expressed in E. Coli.
Specificity Recognizes CTCF 
Formulation State: Ascites
State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Predicted Protein Size 83 kDa
Gene Name CCCTC-binding factor
Background This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors.Tissue specificity: Ubiquitous. Absent in primary spermatocytes.
Synonyms CCCTC-binding factor, CTCFL paralog
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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