TCF3 / E2A (TCF3) Mouse Monoclonal Antibody [Clone ID: 6B8]

Specifications

Product Data
Clone Name	6B8
Applications	ELISA, FC, WB
Recommend Dilution	ELISA: 1/10000. Western Bloting: 1/500 - 1/2000. Flow Cytometry: 1/200 - 1/400.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human TCF3 expressed in E. Coli.
Specificity	Recognizes TCF3
Isotype	IgG1
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	67.6 kDa
Gene Name	transcription factor 3
Database Link	Entrez Gene 6929 Human UniProt ID P15923
Background	Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.
Synonyms	Transcription factor 3, TCF-3, Transcription factor E2-alpha, ITF1, ITF-1
Reference Data

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