JAK3 Mouse Monoclonal Antibody [Clone ID: 5H2]

Specifications

Product Data
Clone Name	5H2
Applications	ELISA, FC, IF, WB
Recommend Dilution	Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000.
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human JAK3 expressed in E. Coli.
Specificity	This antibody reacts to JAK3.
Isotype	IgG1
Formulation	State: Ascites State: Ascitic fluid containing 0.03% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	Human and Mouse.
Gene Name	Janus kinase 3
Database Link	Entrez Gene 3718 Human UniProt ID P52333
Background	JAK3, Janus kinase 3. It is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
Synonyms	Janus kinase 3, JAK-3, L-JAK
Reference Data

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